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File: /data/VThunterPlots/VThunter/index.php
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Backtrace:

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File: /data/VThunterPlots/VThunter/index.php
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VThunter
VThunter
a database for single-cell screening of virus target cells in animal kingdom
...
Lizard

Scientific Name:

Taxonomy:

...
Equid alphaherpesvirus 1

Family: Herpesviridae

Receptor: ITGA4

Receptor ITGA4 information

Summary: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0049 2021.04 10X Genomics Lung Normal 1702 Link
Vthunter_110082 2018.05 Drop-seq Pallium Normal 4187 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of ITGA4 in human tissues   [NCBI]

Expression: Broad expression in spleen (RPKM 22.7), appendix (RPKM 22.2) and 17 other tissues?

Protein expression of ITGA4 in human tissues   [Proteinatlas]